Wednesday 6 August 2008

Nerve, Vascular Damage From Diabetes Reduced By Compound That Helps Rice Grow


Researchers hold found that a compound that helps rice sow grow, springs back into action when brown rice is placed in water overnight in front cooking, significantly reducing the nerve and vascular damage that much result from diabetes.





"You have to allow it get, germinate a little act," says Dr. Robert K. Yu, manager of the Institute of Molecular Medicine and Genetics and Institute of Neuroscience at the Medical College of Georgia. "Some of the active ingredients generated as a result of the germination process ar beneficial to you."





Germinated brown University rice's ability to help diabetics lower their blood sugar has been shown but how it workings remained unknown. New research, published on-line in the Journal of Lipid Research, shows the growth agent acylated steryl glucosides or ASG, helps normalize rakehell sugar and enzymes that are out of whack in diabetes.





"The advantage of knowing this key constituent and its structure is we can now make a net ton of it; you don't have to rely on rice to produce it or eating rice to get this beneficial issue," says Dr. Yu, the paper's corresponding author.





Studies were done in animal models of type 1 diabetes with iI different blood sugar levels that chew over patients' varying blood sugars. They were fed diets of white, brown or pre-germinated brownness rice. Unlike white sir Tim Rice, less-processed brown rice inactive has some of the germ or growth structure that, later on about 24 hours in water, resumes activity. Scientists watched as the resurrected ASG, a growth factor and lipoid, helped normalize metabolism.





"When blood sugar levels increase, the metabolic proportionality changes," says Dr. Seigo Usuki, neurobiologist in the MCG School of Medicine and the paper's first author. "Part of the way we know this growth factor works is by increasing levels of good enzymes that ar decreased in diabetes."





Dr. Usuki is talk about enzymes such as ATPase, which help keep nerve membranes so they can convey electricity and communicate. Decrease of ATPase is a hallmark of the nerve damage that accompanies diabetes. Also reduced in diabetes is